Syphilis
Sexually transmitted infection
Why this is trending
Interest in “Syphilis” spiked on Wikipedia on 2026-02-24.
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Key Takeaways
- Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum .
- The primary stage classically presents with a single chancre, though there may be multiple sores.
- There may also be sores in the mouth or vagina.
- In tertiary syphilis, there are gummas, neurological problems, or heart symptoms.
Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary. The primary stage classically presents with a single chancre, though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. Latent syphilis has no symptoms and can last years. In tertiary syphilis, there are gummas, neurological problems, or heart symptoms. Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases.
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