Norfloxacin
Chemical compound, antibiotic
Why this is trending
Interest in “Norfloxacin” spiked on Wikipedia on 2026-02-25.
Categorised under Science & Nature, this article fits a familiar pattern. Interest in science articles on Wikipedia often follows major discoveries, published studies, or tech industry news.
GlyphSignal tracks these patterns daily, turning raw Wikipedia traffic data into a curated feed of what the world is curious about. Every spike tells a story.
Key Takeaways
- Norfloxacin , sold under the brand name Noroxin among others, is an antibiotic that belongs to the class of fluoroquinolone antibiotics.
- Eye drops were approved for use in children older than one year of age.
- Tendon problems may manifest long after therapy had been completed and in severe cases may result in lifelong disabilities.
- Medical uses The initial approval by the U.
- Antimicrobial agents used in high doses for short periods of time to treat gonorrhea may mask or delay the symptoms of incubating syphilis.
Norfloxacin, sold under the brand name Noroxin among others, is an antibiotic that belongs to the class of fluoroquinolone antibiotics. It is used to treat urinary tract infections, gynecological infections, inflammation of the prostate gland, gonorrhea and bladder infection. Eye drops were approved for use in children older than one year of age.
Norfloxacin is associated with a number of rare serious adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Tendon problems may manifest long after therapy had been completed and in severe cases may result in lifelong disabilities.
It was patented in 1977 and approved for medical use in 1983.
Medical uses
The initial approval by the U.S. Food and Drug Administration (FDA) in 1986 encompassed the following indications:
- Uncomplicated urinary tract infections (including cystitis)
- Complicated urinary tract infections (restricted use)
- Uncomplicated urethral and cervical gonorrhea (however this indication is no longer considered to be effective by some experts due to bacterial resistance)
- Prostatitis due to Escherichia coli.
- Syphilis treatment: Norfloxacin has not been shown to be effective in the treatment of syphilis. Antimicrobial agents used in high doses for short periods of time to treat gonorrhea may mask or delay the symptoms of incubating syphilis.
Although fluoroquinolones are sometimes used to treat typhoid and paratyphoid fever, norfloxacin had more clinical failures than the other fluoroquinolones (417 participants, 5 trials).
In ophthalmology, Norfloxacin licensed use is limited to the treatment of conjunctival infections caused by susceptible bacteria.
Content sourced from Wikipedia under CC BY-SA 4.0
