Marjolein Kriek

Dutch biologist and geneticist

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Key Takeaways

Marjolein Kriek (born 22 November 1973) is a Dutch clinical geneticist at the Leiden University Medical Center.
Sequencing project Leiden University announced the completion of the nine-month-long sequencing of Kriek's genome on 26 May 2008, though the results of the study were published later.
The data set contained significant redundancy, as each base pair was sampled an average of seven to eight times.
At the time, Kriek was one of five or six people to have their entire genome sequenced, the others being James D.
Career and research interests Kriek was born in Leiden and obtained her doctorate in Biomedical Science at Leiden University in 2002.

Marjolein Kriek (born 22 November 1973) is a Dutch clinical geneticist at the Leiden University Medical Center. In 2008, at age 34, she became the first woman and probably the first European to have her total DNA genome sequenced.

Sequencing project

Leiden University announced the completion of the nine-month-long sequencing of Kriek's genome on 26 May 2008, though the results of the study were published later. The study was initiated by Gert-Jan van Ommen of the LUMC team and director of the Center for Medical Systems Biology (CMSB), to gain insight in X-chromosome variability. The data set contained significant redundancy, as each base pair was sampled an average of seven to eight times. The sequencing has been performed in close collaboration with a spin-off company, 'ServiceXS'.

At the time, Kriek was one of five or six people to have their entire genome sequenced, the others being James D. Watson, Craig Venter, two Yoruba men and possibly Dan Stoicescu of Switzerland.

Career and research interests

Kriek was born in Leiden and obtained her doctorate in Biomedical Science at Leiden University in 2002. Her graduate studies included mutation screening in intellectually disabled people. Kriek's subsequent research interests similarly focussed on the diagnosis and clinical significance of genomic imbalances and micro rearrangements as the causes of developmental delay, intellectual disability and congenital syndromes.