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Karl Landsteiner

Karl Landsteiner

Austrian immunologist (1868–1943)

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2026-01-27Peak: 2822026-02-25
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Key Takeaways

  • Karl Landsteiner ( German: [kaʁl ˈlantˌʃtaɪnɐ] ; 14 June 1868 – 26 June 1943) was an Austrian-American biologist, physician, and immunologist.
  • He had distinguished the main blood groups in 1901, having developed the modern system of classification of blood groups from his identification of the presence of agglutinins in the blood.
  • Wiener, he identified the Rhesus factor, thus enabling physicians to transfuse blood without endangering the patient's life.
  • He received the Aronson Prize in 1926.
  • He was posthumously awarded the Lasker Award in 1946, and has been described as the father of transfusion medicine.

Karl Landsteiner (German: [kaʁl ˈlantˌʃtaɪnɐ]; 14 June 1868 – 26 June 1943) was an Austrian-American biologist, physician, and immunologist. He emigrated with his family to New York in 1923 at the age of 55 for professional opportunities, working for the Rockefeller Institute.

He had distinguished the main blood groups in 1901, having developed the modern system of classification of blood groups from his identification of the presence of agglutinins in the blood. In 1937, with Alexander S. Wiener, he identified the Rhesus factor, thus enabling physicians to transfuse blood without endangering the patient's life. With Constantin Levaditi and Erwin Popper, he discovered the polio virus in 1909. He received the Aronson Prize in 1926. In 1930, he received the Nobel Prize in Physiology or Medicine. He was posthumously awarded the Lasker Award in 1946, and has been described as the father of transfusion medicine.

Early life and education

He was born into a Jewish family. His father Leopold Landsteiner (1818–1875), a renowned Viennese journalist and editor-in-chief of Die Presse, died at age 56, when Karl was 6. The boy became very close to his mother Fanny (née Hess; 1837–1908). After graduating with the Matura exam from a Vienna secondary school, he took up the study of medicine at the University of Vienna. Landsteiner wrote his doctoral thesis in 1891. While still a student he published an essay on the influence of diets on the composition of blood.

From 1891 to 1893, Landsteiner studied chemistry in Würzburg under Hermann Emil Fischer, in München, Eugen Bamberger and in Zürich under Arthur Rudolf Hantzsch. He had a number of publications from that period, some of them in co-operation with his professors.

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